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Pandemic

HIV/AIDS

Human Immunodeficiency Virus (HIV)

42.0M

estimated deaths

Period

1981–Ongoing

Origin

Democratic Republic of Congo

Death range

40.0M–45.0M

Infected

85.0M

Overview

HIV/AIDS emerged in the early 1980s and became one of the most destructive pandemics in history. The virus attacks the immune system, leaving the body vulnerable to opportunistic infections. Sub-Saharan Africa has been hardest hit, with some countries seeing 25–30% adult infection rates. Antiretroviral therapy (ART) has transformed HIV from a death sentence to a manageable chronic condition, but the pandemic continues with ~38 million people currently living with the virus.

Historical Timeline

1981
First cases identified (USA)
1995
Peak deaths before ARVs
2020
Ongoing — ~38M living with HIV

Symptoms

Rapid weight loss
Recurring fever
Night sweats
Swollen lymph nodes
Opportunistic infections (TB, pneumonia)

Affected Regions

Southern Africa (epicentre)
Sub-Saharan Africa
USA
Brazil
India
China

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Data sourced from WHO, CDC, and peer-reviewed academic sources. Death toll estimates may vary across sources.

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Data: WHO · CDC · UNAIDS · IAEA · Britannica

HIV/AIDS — 42M Deaths (1981–present) | PlaguAtlas