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Pandemic

Malaria (ongoing)

Plasmodium falciparum

70.0M

estimated deaths

Period

1900–Ongoing

Origin

Sub-Saharan Africa

Death range

60.0M–80.0M

Infected

2.0B

Overview

Malaria is a mosquito-borne infectious disease that has plagued humanity for millennia. Caused by Plasmodium parasites transmitted by female Anopheles mosquitoes, it kills approximately 600,000 people per year, predominantly children under 5 in Sub-Saharan Africa. In the 20th and 21st centuries combined, it has killed an estimated 50–100 million people. A vaccine (RTS,S/AS01) was approved in 2021.

Historical Timeline

2023
~600K deaths/year ongoing

Symptoms

Cyclical fever and chills
Severe headache
Vomiting
Jaundice
Seizures (cerebral malaria)

Affected Regions

Sub-Saharan Africa
South Asia
Southeast Asia
Amazon Basin

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Data sourced from WHO, CDC, and peer-reviewed academic sources. Death toll estimates may vary across sources.

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Data: WHO · CDC · UNAIDS · IAEA · Britannica

Malaria (ongoing) — 70M Deaths (1900–present) | PlaguAtlas